2023

Kolabas Z.I.,…, Gokce O., et al., Erturk A., (2023) Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation Cell

Androvic P, Schifferer M, Perez Anderson K, Ji H, Liu L, Besson-Girard S, Knoferle J, Simons M, Gokce O., (2023) Spatial Transcriptomics correlated Electron Microscopy Nature Comm

2022

Benakis C.,…, Gokce O., et al., (2022) T cells modulate the microglial response to brain ischemia Elife

Paolicelli R., .,…, Gokce O., et al., (2022) Defining Microglial States and Nomenclature: A Roadmap to 2030 Neuron

Brandhofer M.,…, Gokce O., et al., Bernhagen J., (2022) Heterocomplexes between the Atypical Chemokine MIF and the CXC-Motif Chemokine CXCL4L1 Regulate Inflammation and Thrombus Formation CMLS

Cantuti-Castelvetri L., Gokce O., Simons M., (2022) Reparative inflammation in multiple sclerosis Seminars in immunology, 101630

Jocher G.,…, Kaya T., Gokce O., et al., Lichtenthaler S., (2022) ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion EMBO Reports 23:e54305

Kaya T. *, Mattugini N. *, Liu L. *, et al., Gokce O.#, Simons M.#, (2022) CD8+ T cells induce interferon-responsive oligodendrocytes in white matter aging. Biorxiv

Kolabas Z.I.,…, Gokce O., et al., Erturk A.  (2022) Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation Biorxiv

2021

Lui L., Besson-Girard S., et al., Gokce O. (2021) Dissociation of microdissected mouse brain tissue for artifact free Single-Cell RNA Sequencing. StarProtocols

Brandhofer M.,…, Gokce O., et al., Bernhagen J., (2021) Heterocomplexes between the Atypical Chemokine MIF and the CXC-Motif Chemokine CXCL4L1 Regulate Inflammation and Thrombus Formation Biorxiv

Benakis C.,…, Gokce O., et al., (2021) T cells modulate the microglial response to brain ischemia Biorxiv

Gouna G, Klose C, Bosch-Queralt M, Liu L, Gokce O, et al., Simons M., (2021) TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination. JEM.

Safaiyan S.*, Besson-Girard S.*, Kaya T, Cantuti-Castelvetri L, Liu L, Ji H, et al., Gokce O.#, Simons M.# (2021) White matter aging drives microglial diversity. Neuron

2020

Kontos C.,..., Gokce O. et al., Bernhagen J., (2020) Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting. Nature Communications. 11, Article number: 5981

Cantuti-Castelvetri, L., Ojha, R.,..., Tuğberk K.,… Gokce O., et al., (2020)  Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system. Science

Stanley G.*, Gokce O.*, Malenka R.C., Südhof T.C., and Quake S.R., (2020) Discrete and Continuous Cell Identities of the Adult Murine Striatum. Neuron 105 (4), 688-699. e8

2019

Kapurniotu A., Gokce O., Bernhagen J., (2019) The Multitasking Potential of Alarmins and Atypical Chemokines. Frontiers in Medicine

2018

Wang W., Penland L., Gokce O., Croote D., and Quake S.R., (2018) High fidelity hypothermic preservation of primary tissues in organ transplant preservative for single cell transcriptome analysis. BMC Genomics Feb 19: 140.

Zhang B., Gokce O., Hale D.W., Brose N., and Sudhof T.C., (2018) Autism-Associated Neuroligin-4 Mutation Selectively Impairs Glycinergic Synaptic Transmission in Mouse Brainstem Synapses. JEM 215, 6.

2017

Chen L.Y., Jiang M., Zhang B., Gokce O., and Sudhof T.C., (2017) Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins. Neuron 94 (3), 611-625. e4.

2016

Gokce O.*, Stenley G.*, Treutlein B*., Neff N.F., Camp G.J., Malenka R.C., Rothwell P.E., Fuccillo M.V., Südhof T.C. and Quake S.R., (2016) Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNAseq. Cell Reports 16, 1–12

Zhang B., Seigneur E., Wei P., Gokce O., Morgan J., and Sudhof T.C., (2016) Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held. Molecular Psychiatry 00, 1–9

2015

Fuccillo M.*, Foldy C.*, Gokce O.*, Rothwell P.E., Sun G.L., Robert C.M. and Südhof T.C., (2015) Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms. Neuron 87, 326–340.

Zhang B., Chen L.Y., Liu X., Maxeiner S., Lee S.J., Gokce O., and Südhof T.C., (2015) Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses. Neuron 87, 781–796.

2014

Treutlein B*., Gokce O.*, Quake S.R., and Südhof T.C., (2014) Cartography of Neurexin Diversity Mapped by Single-Molecule Long-Read mRNA Sequencing. (PNAS) 111 (13) E1291-E1299;

Smith M.R., …, Gokce, O., et al., (2014) A Potent and Selective Sirtuin 1 Inhibitor Alleviates Pathology in Multiple Animal and Cell Models of Huntington’s Disease. Hum. Mol. Genet. PMID: 24436303

Rothwell P.E., Fuccillo M.V., Maxeiner S., Hayton S.J., Gokce O., Lim B.K., Fowler S.C., Malenka R.C., and Südhof T.C., (2014) Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors. Cell; 158(1):198–212.

2013

Rosa, S., Benicchi, T., Bettinetti, L., Ceccarelli, I., Diodato, E., Federico, C., Gokce, O., et al., (2013) Fused 3‑Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity. ACS Med. Chem. Lett. 4 (10), pp 979–984.

Gokce O., & Südhof T.C., (2013) Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation, Journal of Neuroscience, 33(36), 14617–14628. 

Older

Zucker B., Kama J. A., Kuhn A., Thu D., Lianna R., Dunah A.W., Gokce O., et al., (2012) Decreased Lin7b Expression in Layer 5 Pyramidal Neurons May Contribute to Impaired Corticostriatal Connectivity in Huntington Disease, J Neuropathol Exp Neurol. 69(9), 880–895.

Seredenina T.*, Gokce O.*, Luthi-Carter R., (2011) Decreased striatal RGS2 expression is neuroprotective in Huntington’s disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation. PLoS ONE, 4(4), e5292.

Luthi-Carter R., Taylor D. M., Pallos J., Lambert E., Amore A., Parker A., Gokce O., et al., (2010) SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. PNAS 107(17), 7927–32. 

Gambazzi L.*, Gokce O.*, Seredenina T., Katsyuba E., Runne H., Markram H., Giugliano M., Luthi-Carter R., (2010) Diminished Activity-Dependent Brain-Derived Neurotrophic Factor Expression Underlies Cortical Neuron Microcircuit Hypoconnectivity Resulting from Exposure to Mutant Huntingtin Fragments, JPET 335(1), 13–22. 

 Jan A., Gokce O., Luthi-Carter R., and Lashuel H. A., (2008) "The Ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of Aβ aggregation, fibrillogenesis, and toxicity" J Biol Chem 283 (42), 28176-28189.

Gokce O., Runne H., Kuhn A. & Luthi-Carter R., (2009) “Short-term striatal gene expression responses to   brain-derived neurotrophic factor are dependent on MEK and ERK activation" PLoS ONE 4 (4), e5292.

Rudinskiy N., Kaneko Y., Beesen A.A., Gokce O., Régulier E., Déglon N., Luthi-Carter R., (2009) Diminished Hippocalcin Expression in Huntington’s Disease Brain does not Account for Increased Striatal Neuron Vulnerability as Assessed in Primary Neurons. Journal of Neurochemistry, 111(2).

Runne H., Régulier E., Kuhn A., Zala D., Gokce O., Perrin V., Sick B., Aebischer P., Déglon N. & Luthi-Carter R., (2008) "Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome are not dependent on brain circuitry" Journal of Neuroscience, 28 (39), 9723-9731.

Guzeloglu-Kayisli O., Kayisli UA., Amankulor NM., Voorhees JR., Gokce O., DiLuna ML., Laurans MS., Luleci G., Gunel M., (2004) "Krev1 interaction trapped-1/cerebral cavernous malformation-1 protein expression during early angiogenesis." J Neurosurg 100 481-7. 

* Indicates equal contribution

#Correspondence